MERS-COV (23): SAUDI ARABIA (ASIR) ANIMAL RESERVOIR, HUMAN CONTACT, OIE, REQUEST FOR INFORMATION

Posted on 22ND APR 2017
tagged MERS-CoV, Saudi Arabia

A ProMED-mail post
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International Society for Infectious Diseases
http://www.isid.org

Date: Thu 20 Apr 2017
Source: OIE, WAHID weekly disease information 2017; 30 (16) [edited]
http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review?page_ref...

MERS-CoV, Saudi Arabia
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Information received on [and dated] 20 Apr 2017 from Dr Mohammed Alblowi, Director General, Diagnostic Veterinary Laboratories, Ministry of Environment, Water and Agriculture, Riyadh , Saudi Arabia

Summary
Report type: Follow-up report No. 5
Date of start of the event: 29 Dec 2015
Date of confirmation of the event: 20 Jan 2016
Report date: 20 Apr 2017
Date submitted to OIE: 20 Apr 2017
Reason for notification: Emerging disease
Morbidity: 2.36 percent
Mortality: 0 percent
Zoonotic impact: No
Causal agent MERS-CoV

New outbreaks (1)
Outbreak 1: Mahail, 'ASIR
Date of start of the outbreak: 24 Mar 2017
Outbreak status: Resolved (15 Apr 2017)
Epidemiological unit: Farm
Affected animals
Species/Susceptible/Cases/Deaths/Destroyed/Slaughtered
Camelidae/ 3/ 1/ 0/ 0/ 0

Epidemiology
Source of the outbreak(s) or origin of infection: Unknown or inconclusive
Epidemiological comments: This outbreak is associated with a human case. All previous outbreaks were resolved.

Control measures
1. Measures applied: Movement control inside the country, Screening, Disinfection / Disinfestation, Traceability, Quarantine, Surveillance outside containment and/or protection zone, Vaccination permitted (if a vaccine exists), No treatment of affected animals
2. Measures to be applied: No other measures
Diagnostic test results
Laboratory name and type: Veterinary Diagnostic Laboratory, Riyadh (National laboratory)
Species/Test/Test date/Result
Camelidae/real-time PCR/ 02 Apr 2017/Positive

[The location of the outbreak can be seen on the interactive map at the source URL above].

--
Communicated by:
ProMED-mail

[In view of the included epidemiological comment, it may be assumed with high probability that the mentioned relevant human case is the one described in posting 20170306.4875743, which referred to 3 new human cases as specified in Saudi Arabia's Ministry of Health report of 20 Feb 2017 (at http://www.moh.gov.sa/en/CCC/PressReleases/Pages/statistics-2017-02-20-0...). The said MOH daily report addressed new human cases during the preceding 24 hours.

The relevant case (No 11) was referred to as a "63 year old Saudi male" of Saudi nationality, "non-healthcare worker from Mahail Aseer [`Asīr region], noted to be in a critical condition at the time of confirmation. Classified as a primary case with a history of direct contact with camels in the 14 days preceding onset of illness". No definite fate of the case was available, but subscribers are referred to Mod.MPP's comment there, stating that "according to the Saudi MOH MERS website there was the addition of a fatality in the tallies from 20-22 Feb 2017, but no information was available on this fatality - presumably reported on 21 Feb 2017?".

To assess the zoonotic significance of the current test results in 3 sampled camels from Mahail,'ASIR (same address as of the mentioned patient), with which the patient was reportedly in contact "during the 14 days preceding onset of illness", the date of the onset of his illness, date of sampling of the 3 camels and their respective age(s) will be helpful. Notably, the report states: "Zoonotic impact: No". This is in need of clarification.

The following updated summary of Saudi Arabia's information about the confirmed MERS infections in camels since the start of testing (reportedly, 29 Dec 2015), is available in WAHID's archive (at http://www.oie.int/wahis_2/temp/reports/en_fup_0000023594_20170420_16173..., including a map of all locations):

Total outbreaks = 14 (Submitted)
Species/ Susceptible/ Cases/ Deaths/ Destroyed/ Slaughtered
Camelidae/ 663/ 93/ 0/ 0/ 0

Details on the actual performance of the (6) control measures specified as being applied in Saudi Arabia to address MERS in animals, will be helpful (no MERS vaccine for camels is yet available).

The following update of global MERS statistics in animals is based upon OIE data:

Between October 2013 and April 2017 MERS-CoV was detected in camels in:
Saudi Arabia (14), http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...
Qatar (3), http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...
Iran (3), http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...
Kuwait (2), http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...
Jordan (2), http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...
Oman (5) http://www.oie.int/wahis_2/public/wahid.php/Reviewreport/Review/viewsumm...

In the UAE, the involvement of camels is based upon information on human infections related to the consumption of raw camel milk (see http://www.who.int/csr/don/26-january-2016-mers-are/en/). See also https://wwwnc.cdc.gov/eid/article/20/4/13-1746_article.

In October 2012 MERS was reported from a bat in Saudi Arabia. It was detected also in milk samples in Qatar.

Most of the (nearly 2000; at least, 739 deaths) human MERS cases are reported from Middle-Eastern countries, predominantly Saudi Arabia. - Mod.AS

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/promed/p/2984.]

See Also

MERS-CoV (21): Egypt, animal reservoir, camel, ex Sudan, control, RFI 20170405.4948727
MERS-CoV (14): Saudi Arabia 20170306.4875743
MERS-CoV (18): Africa, animal reservoir, camels, 2015, research 20170331.4939980
2016
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MERS-CoV (90): Saudi Arabia (RI), camel association, UAE 20160808.4402381
MERS-CoV (59): animal reservoir, review 20160610.4275921
MERS-CoV (40): Egypt, animal reservoir, camel, ex Sudan, susp. 20160316.4097730
MERS-CoV (39): Saudi Arabia (RI) 20160315.4095267
MERS-CoV (38): Saudi Arabia (RI, MK), RFI 20160314.4092319
MERS-CoV (37): Saudi Arabia (QS, HA) 20160313.4090021
MERS-CoV (36): Saudi Arabia, RFI 20160312.4088330
MERS-CoV (35): Saudi Arabia, Qatar ex Saudi Arabia, WHO 20160311.4085518
MERS-CoV (34): Saudi Arabia, nosocomial, RFI 20160310.4083896
MERS-CoV (33): Saudi Arabia, nosocomial 20160309.4076391
MERS-CoV (32): Saudi Arabia (RI) 20160306.4072878
MERS-CoV (31): Saudi Arabia, Kenya serosurvey 20160305.4070643
MERS-CoV (30): Saudi Arabia (QS) WHO 20160303.4066494
MERS-CoV (29): Saudi Arabia (RI) 20160229.4057451
MERS-CoV (28): Saudi Arabia (AS) 20160227.4054878
MERS-CoV (27): Saudi Arabia (RI), RFI 20160226.4053654
MERS-CoV (26): Saudi Arabia (NJ,HA) 20160225.4049798
MERS-CoV (25): Saudi Arabia, RFI 20160223.4045089
MERS-CoV (24): Qatar ex Saudi Arabia, Saudi Arabia (RI) RFI 20160222.4041719
MERS-CoV (23): Saudi Arabia (RI) 2015 outbreak, RFI 20160220.4036190
MERS-CoV (22): Saudi Arabia (RI) RFI 20160218.4028850
MERS-CoV (21): Saudi Arabia, animal reservoir, camel, comment 20160216.4023772
MERS-CoV (20): Saudi Arabia (NJ,RI) 20160212.4016509
MERS-CoV (19): Saudi Arabia, animal reservoir, camel, prevention, RFI 20160204.3995194
MERS-CoV (18): Saudi Arabia, animal reservoir, camel, vaccination, comment 20160203.3990284
MERS-CoV (17): Saudi Arabia (MK) WHO 20160203.3987728
MERS-CoV (16): Saudi Arabia (MK) animal reservoir, OIE, RFI 20160201.3985175
MERS-CoV (15): Saudi Arabia (RI) 20160201.3985046
MERS-CoV (13): Saudi Arabia (RI) 20160127.3970964
MERS-CoV (12): UAE, Oman, Saudi Arabia, WHO 20160126.3967808
MERS-CoV (11): Saudi Arabia, animal reservoir, camel, vaccination, comment 20160126.3966528
MERS-CoV (10): Saudi Arabia (MK), Thailand ex Oman, RFI 20160125.3964309
MERS-CoV (09): Saudi Arabia, animal reservoir, camel, vaccination considered 20160125.3963370
MERS-COV (08): Thailand ex Oman, Saudi Arabia corr 20160124.3962172
MERS-CoV (07): Saudi Arabia 20160123.3959982
MERS-CoV (06): UAE (AZ) 20160114.3937314
MERS-COV (03): Korea, virus mutation 20160108.3921223
MERS-COV (01): Oman, Saudi Arabia 20160105.3911188
2015
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MERS-COV (167): acute management and long-term survival 20151231.3904300
MERS-CoV (01): Saudi Arabia, new cases, new death 20150104.3069383
2014
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MERS-CoV (69): Saudi Arabia, new case, RFI 20141230.306305
MERS-CoV (01): Bangladesh, KSA, Algeria, UAE, Iran, WHO, RFI 20140616.2541707
MERS-CoV - Eastern Mediterranean (82): anim res, camel, seroepidemiology 20140613.2537848
MERS-CoV - Eastern Mediterranean (01): Saudi Arabia, UAE, Oman, WHO 20140103.2150717
2013
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MERS-CoV - Eastern Mediterranean (106): animal reservoir, camel, Qatar, OIE 20131231.2145606
MERS-CoV - Eastern Mediterranean: Saudi Arabia, new case, RFI 20130518.1721601
Novel coronavirus - Eastern Mediterranean (29): MERS-CoV, ICTV nomenclature 20130516.1717833
Novel coronavirus - Eastern Mediterranean: bat reservoir 20130122.1508656
2012
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Novel coronavirus - Eastern Mediterranean (06): comments 20121225.1468821
Novel coronavirus - Eastern Mediterranean: WHO, Jordan, conf., RFI 20121130.1432498
Novel coronavirus - Saudi Arabia (18): WHO, new cases, cluster 20121123.1421664
Novel coronavirus - Saudi Arabia: human isolate 20120920.1302733
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