EBOLA UPDATE (05): NEWS, VACCINE, FUNDING, DOCUMENTARY FILMS

Posted on 30TH JAN 2017
tagged Ebola, Liberia; Sierra Leone

A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org

In this update:
- News
Liberia
West Africa - People's science
- Vaccine
Recombinant vesicular stomatitis virus vaccine
- Funding
Sierra Leone
- Documentary film
HBO, human stories from the outbreak

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26 Jan 2017 Liberia: USAID program to support Ebola survivors takes off
http://allafrica.com/stories/201701260566.html
[John Snow Incorporated (JSI) Research and Training Institute on Tue 24 Jan 2017 began the United States Agency for International Development (USAID)-funded Ebola Transmission Prevention and Survivor Services (ETP&SS) program at a resort in Monrovia.
The program, which is being implemented by the Advancing Partners and Communities project, was launched by Tolbert Nyenswah, Deputy Health Minister for Public Health Emergencies and Epidemic Control.
In Liberia, The ETP&SS program will concentrate its health interventions on 4 high-priority counties: Montserrado, Margibi, Bong, and Lofa.] [Survivors of Ebola virus disease (EVD)] continue to experience psychological conditions which require specialized medical attention that is difficult to access either because of stigma and discrimination or because expertise to manage such cases is limited in Liberia. Thus, this is an important program being launched by USAID. - Mod.LK]

26 Jan 2017 West Africa: 'People's Science' - How West African communities fought the Ebola epidemic and won
http://allafrica.com/stories/201701270636.html
[Three years on from the start of the West African Ebola epidemic, lessons are still being learned. And the most surprising are not coming from the scientists, but from the affected communities themselves; about how, with hardly any help, they tackled the virus and won."...
How did they do it?
"People's Science"; the fact that people in the affected areas used their experience and common sense to figure out what was happening, and began to change their behaviour accordingly.
Paul Richards, a veteran British anthropologist, now teaching at Njala University in Sierra Leone, ... is convinced the main driver of the reduction [of disease] was what he calls "People's Science"; the fact that people in the affected areas used their experience and common sense to figure out what was happening, and began to change their behavior accordingly."...
He told a recent meeting at London's Chatham House: "One of the pieces of evidence which makes me think that local response was significant is that the decline 1st occurred where the epidemic began, so that the longer the experience you had of the disease, the more likely you are to see tumbling numbers. So, someone was learning... People ask me, 'How long does it take to learn?' And we don't know, but on the basis of this case study, it's about 6 weeks." (Byline: Elizabeth Blunt)
[This is a study that emphasizes the importance of working at the local level, even to control a widespread outbreak. According to this study, it was estimated to take 6 weeks for people to learn and adopt safe practices, but it is hoped that learning curve will be faster if there is another outbreak of Ebola. - Mod.LK]

Vaccines
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26 Jan 2017: Recombinant vesicular stomatitis virus vaccine elicits anti-Ebola seroconversion
http://www.2minutemedicine.com/recombinant-vesicular-stomatitis-virus-va...
[The Ebola virus outbreak of 2014 has prompted renewed interest in development of a vaccine that could be used for pre-exposure prophylaxis. This study tested the use of a rVSV [recombinant vesicular stomatitis virus] live attenuated recombinant virus vaccine that was genetically engineered to replace the VSV glycoprotein with that of the Zaire strain of Ebola virus (ZEBOV). The results of 2 placebo-controlled, dose-escalation trials of the rVSV-ZEBOV are reported by this paper.
By day 28, all recipients of an rVSV vaccine, at each of the 3 doses tested, demonstrated seroconversion against an Ebola virus glycoprotein.
Anti-Ebola glycoprotein titers were higher in patients who received a 20 million or 100 million plaque-forming unit (PFU) dose than in patients who received the 3 million PFU dose.
Citation.
Regules JA, Beigel EL, Paolino KM, et al. (26 Jan 2017). N Engl J Med 2017; 376:330-341 DOI: 10.1056/NEJMoa1414216 http://www.nejm.org/doi/full/10.1056/NEJMoa1414216]

Funding
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24 Jan 2017 Sierra Leone: Millions of Ebola Relief Funds Misappropriated in Sierra Leone
https://face2faceafrica.com/article/ebola-funds-sierra-leone
[Investigations have revealed that millions of dollars set aside to facilitate the fight against the Ebola outbreak in Sierra Leone have been misappropriated. The internal audit report says that at least USD 14 million allocated for fighting Ebola [Ebola virus disease (EVD)] in 2014 could not be accounted for, even as the survivors of the deadly epidemic continue to wallow in poverty, unable to pick up the pieces, reports the BBC.
The stolen cash includes millions of high-risk health hazard allowances for medical workers who risked their lives to offer services to victims of the disease. Investigations revealed that the allowances, amounting to USD 4 million, were never paid. "I was signing for 2 million leone [USD 360] a month, but I only received 1.5 million leone," Andrew Bockarie, a hygienist and former volunteer, says.
In 2014, health volunteers participating in the fight against [EVD] in Sierra Leone, staged mass protests at Kenema Hospital over delayed payments. Those in charge of disposing bodies of the deceased brought corpses from the morgue and dumped them at the hospital's entrance, demanding unpaid allowances.
Bockarie, who took part in the protests, says he didn't receive any allowances for 8 months, which totals to 4 million leone. Sierra Leone's Auditor General, Madam Lara Taylor-Pearce, recently revealed that some of the misappropriated money is still missing 2 years down the line and nothing has been done to bring the culprits to justice. In fact, only a handful of civil servants have so far been suspended.
She further admitted that there was no accountability in the procurement of ambulances and other medical supplies, adding that most of the ambulances paid for were never supplied.]

Documentary films
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26 Jan 2017: HBO Documentary Films is uncovering the human stories behind the Ebola outbreak
http://www.ryot.org/blog/hbo-documentary-films-is-uncovering-the-human-s...
[HBO Documentary Films is directing its attention towards the West African Ebola outbreak next month [February 2017] by releasing a special presentation of 3 short films about the subject, including "Ebola: The Doctors' Story," "Orphans of Ebola" and the Academy Award-nominated "Body Team 12".
Each documentary short follows a new perspective and subject, trailing the doctors, response teams and orphaned children who struggle against the rapidly spreading disease. Individual film descriptions [can be found at the URL above], courtesy of HBO Documentary Films.]

[Compiled by: Celeste Whitlow ]

--
Communicated by:
ProMED-mail

[A map showing the distribution of EVD cases as of 27 Mar 2016 can be seen at http://apps.who.int/ebola/sites/default/files/thumbnails/image/sitrep_ca....

ProMED HealthMaps:
Liberia http://healthmap.org/promed/p/54
Guinea http://healthmap.org/promed/p/45
Sierra Leone http://healthmap.org/promed/p/46 - Mod.LK]

See Also
Ebola update (04): research 20170123.4786222
Ebola update (03): news, research 20170115.4767977
Ebola update (02): news, research, vaccine, comment 20170108.4750411
Ebola update (01): News, research, vaccine 20170103.4738060
2016
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Ebola update (72): vaccine, research, NGO, media 20161226.4724859
Ebola update (71): research, economy 20161218.4706276
Ebola update (70): news, research, economy, funding 20161211.4690740
Ebola update (69): news, NGO, research, economy, funding, vaccine 20161204.4675615
Ebola update (68): news, economy 20161127.4657148
Ebola update (67): news, research, funding 20161120.4642402
Ebola update (66): news, research, funding, economy 20161115.4629793
Ebola update (65): news, research, commentary, economy, funding, vaccine 20161106.4609611
Ebola update (64): news, research 20161030.4595759
Ebola update (63): news, research 20161023.4579436
Ebola update (62): news, research, treatment, funding 20161017.4564066
Ebola update (61): news, funding, economy 20161009.4547627
Ebola update (60): news, research, economy 20161002.4531285
Ebola update (59): news, research, funding 20160925.4514591
Ebola update (58): news, research, funding, vaccine 20160918.4497393
Ebola update (57): news, research, funding 20160911.4481043
Ebola update (56): news, vaccine, research 20160904.4465145
Ebola update (55): research, funding 20160828.4446844
Ebola update (54): rapid test recall, nurse, research 20160821.4431433
Ebola update (53): Guinea, research 20160814.4415032
Ebola update (52): funding, research 20160808.4400521
Ebola update (51): funding, research, miscellaneous 20160731.4383179
Ebola update (50): Liberia, Sierra Leone, research 20160724.4366266
Ebola update (49): Sierra Leone, research, history 20160717.4350351
Ebola update (48): CDC, research, funding, economy 20160710.4336146
Ebola update (47): Liberia, US preparedness, funding, research 20160703.4323924
Ebola update (46): Liberia, Sierra Leone, treatment comment, research, funding 20160626.4310569
Ebola update (45): Liberia, vaccine, treatment, funding, research 20160619.4296380
Ebola update (44): Liberia, WHO, funding, research 20160612.4283379
Ebola update (43): digital wallet response, Guinea, diagnostic assay 20160605.4266788
Ebola update (42): Guinea, vaccine, research 20160529.4253046
Ebola update (41): update, funding 20160522.4238249
Ebola update (40): Liberia, Sierra Leone, research, vaccines 20160514.4222416
Ebola update (39): Guinea persistence in semen, Liberia, research, vaccine 20160508.4209313
Ebola update (38): WHO sitrep. evolution rate, Liberia, Sierra Leone, research 20160501.4195742
Ebola update (37): Guinea, Liberia, diagnostics, vaccine, funding, research 20160427.4187854
Ebola update (36): Guinea, Liberia, vaccine, research 20160421.4172812
Ebola update (35): vaccine, comment 20160418.4167038
Ebola update (34): Guinea, Liberia, comment, vaccine funding 20160417.4165862
Ebola update (33): Guinea, Liberia, Sierra Leone, research, funding, vaccine 20160413.4158203
Ebola update (32): Liberia, Guinea, support 20160410.4150454
Ebola update (31): Liberia, Guinea re-emergence, research, funding 20160406.4142990
Ebola update (30): Liberia re-emergence, Uganda NOT, RFI 20160404.4136987
Ebola update (29): Liberia re-emergence, Guinea contacts, news, RFI 20160402.4134878
Ebola update (28): news, research, vaccine 20160330.4128527
Ebola update (27): Ebola Reston virulence, Africa suspicious deaths RFI, news 20160327.4121931
Ebola update (26): Guinea flare-up, Liberia 20160324.4114807
Ebola update (25): Guinea flare-up, Liberia, Sierra Leone, research 20160320.4107350
Ebola update (24): Guinea, confirmed 20160317.4101955
Ebola update (23): comment, pregnant women, news, research 20160316.4098040
Ebola update (22): long-term sequelae, news, research 20160313.4090091
Ebola update (21): Sierra Leone, herd immunity, possible new drug 20160310.4081498
Ebola update (20): new antiviral, prevention 20160306.4073116
Ebola update (19): WHO, relapse in UK (Scotland), prevention, research, funding 20160302.4064754
Ebola update (18): WHO, susp, research, funding, NGO, corr 20160229.4058786
Ebola update (17): UK nurse readmitted, EVD survivor complications, research 20160224.4047552
Ebola update (16): WHO comment, funding, vaccine 20160221.4039174
Ebola update (15): WHO response comment, vaccine 20160218.4030271
Ebola update (14): research, funding, vaccine, NGO 20160214.4021318
Ebola update (13): rapid test, research, funding 20160210.4010884
Ebola update (12): Sierra Leone, research, funding, vaccine 20160207.4002006
Ebola update (11): Sierra Leone, new case, controversy 20160203.3990396
Ebola update (10): Sierra Leone, vaccine, funding 20160131.3981594
Ebola update (09): funding, correction 20160127.3970963
Ebola update (08): Sierra Leone, vaccine, research, video 20160124.3962240
Ebola update (07): Sierra Leone, 2nd new case 20160121.3955860
Ebola update (06): 5 mysteries about EVD, Sierra Leone new case, followup 20160117.3944673
Ebola update (05): WHO declares Liberia free, Sierra Leone new case 20160115.3938471
Ebola update (04): WHO, prevention, research, drugs & vaccines 20160113.3933860
Ebola update (03): WHO, prevention, survivors, stigma, research, drugs, vaccines 20160110.3924235
Ebola update (02): WHO, monitoring, lessons, research 20160106.3915785
Ebola update (01): management, vaccine, treatment, monitoring 20160103.3908196
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